Butyl resorcinol solubility. 27 μM. Kopcinol)ออกฤทธิ์ เพื่อให้ผิวกระจ่างใสขึ้น ด้วยการลดการทำงานของ Tyrosinase However, its poor solubility, low stability, and strong irritation to the skin limit its application. for the product 4-Butylresorcinol 99. It is one of three isomeric benzenediols, the 1,3-isomer (or meta -isomer). Limited water solubility. Mechanistic studies of the inactivation of tyrosinase by resorcinol Depigmenting action of hydroquinone depends on disruption of fundamental cell processes Glutathione SpecWhite® 4BR is 4-Butylresorcinol, which is insoluble in water, soluble in ethanol and most organic solvents. 4-Butyl Resorcinol is a synthetic organic compound that has gained significant attention in various industries, particularly in 4-Butylresorcinol (Butylresorcinol) is a phenol derivative which can inhibit tyrosinase with IC50 of 11. Each Beginning with n-butyl resorcinol, the percentage of inhibitory effect increases until at n-heptyl and n-octyl resorcinol there is a total loss of disinfecting power. In this study, 4-nBR was prepared into 4-n-butylresorcinol nanoemulsion (4-nBR The toxic effects of resorcinol are related to dose, as seen from the data below. In this study, 4-nBR was prepared into 4-n-butylresorcinol nanoemulsion (4-nBR 4-Butyl Resorcinol Powder is considered the most potent inhibitor of tyrosinase, which is why it is used in cosmetics as a depigmenting agent China 4-Butylresorcinol CAS 18979-61-8 - manufacturer, supplier. PER can be therefore found in many BOC Sciences offers 4-Butylresorcinol (18979-61-8) in bulk, please inquire us to get a quote for 4-Butylresorcinol (18979-61-8). Q. Soluble in most organic solvents such as benzene, toluene, acetone, ethyl acetate, and ethanol. Sample Available. PER can be therefore found in many GfN-Selco Butyl Resorcinol is a chemically derived alkyl resorcinol known for its excellent bioavailability and strong tyrosinase-inhibiting properties. 4-n-butylresorcinol (4-nBR) has a significant effect on skin pigmentation, but its poor solubility, low stability and strong irritation to the Relevant identified uses of the substance or mixture and uses advised against Relevant identified uses 4-Butyl resorcinol was reduced with palladium carbon in methanol. 1% 4-butyl resorcinol cream showed rapid efficacy with excellent tolerability in patients with melasma [177, 180]. - >99% HPLC purity, ideal for cancer research and Augment your research on Biodegradable Polymers with the reliable Clipos™ 4-Butylresorcinol Liposomes from CD Bioparticles Drug Delivery. This document details its SpecWhite® 4BR is 4-Butylresorcinol, which is insoluble in water, soluble in ethanol and most organic solvents. 22 Molecular formula: C10H14O2 CAS No. It is a synthetic compound that is designed to stop melanin production by Activated Resorcinol ™ (4-BUTYL RESORCINOL, E. 1, III, (E), environment-ally hazardous Classification code Danger label(s) Solubility of Benzene-1,3-diol (C 6 H 6 O 2) Benzene-1,3-diol, also known as resorcinol, exhibits an interesting solubility profile that is influenced by its unique structure. g. Recommen-ded pH range is 6. Vivinol by James Robinson Speciality Ingredients is a skin lightening chemical that reduces melanin pigmentation, bloches, and freckles in cosmetic lotions. However, these two compounds were unstable due to the oxidation 4-Butylresorcinol (4-n-Butylresorcinol, Rucinol) is a potent inhibitor of <b>tyrosinase</b> and is used in cosmetics as a depigmenting agent. Aiming to develop the analytical method for resorcinol and 4-n-butyl resorcinol determination, a response surface methodology (RSM) High-purity 4-Butylresorcinol from APExBIO, a reliable skin brightening agent with superior performance for cosmetic and dermatological research Product Description As an leading organization, we are engaged in offering 4-n-butylresorcinol in desired quantities. , Ltd TCI AMERICA Resorcinol, 4-butyl- Synonyms 4-Butylresorcin; 4-Butylresorcinol; 1,3-Dihydroxy-4-n-Butyl Benzene; Category Non-ionic surfactant > Phenol >> Hydrocarbyl Phenol Chemical Resorcinol (1,3- dihydroxybenzene) Phenol derivative with 2 –OH groups Soluble Despite aromatic ring, two hydroxyl groups increase polarity and hydrogen bonding with water. The first one to add to China 4-Butylresorcinol CAS 18979-61-8 - Manufacturer, Supplier. Butyl Resorcinol tends to turn pinkish In the present study, three laboratories independently compared percutaneous absorption and distribution of 4-n-butylresorcinol, using human skin from five donors. Hypopigmenting Overview The official chemical name is 4-n-butyl resorcinol, but generally, everyone likes to simplify writing butyl resorcinol. 4-Butylresorcinol | C10H14O2 | CID 205912 - structure, chemical names, physical and chemical properties, classification, patents, literature, SpecWhite® 4BR is 4-Butylresorcinol, which is insoluble in water, soluble in ethanol and most organic solvents. It is used in cosmetics and personal care 4-butyl resorcinol resorcinol, 4-butyl- Supplier Sponsors BOC Sciences Jiangyin Healthway International Trade Co. Get Short Description: 4-Butyl resorcinol is a derivative of resorcinol, which has certain cytotoxicity and whitening effect, and is a prohibited whitening COA of 4-Butylresorcinol contains the actual results obtained from testing performed as part of quality control. The application of liposomal azelaic acid, 4-n butyl resorcinol and retinol serum enhanced by microneedling for treatment of malar pattern melasma: A case series Article Full 4-Butyl Resorcinol, a highly effective skin whitening and brightening agent, has the following effects: 1. Quality assured with certificates and reports. Resorcinol The 0. Hyperpigmentation is believed to be related to the resorcinol derivative 4-n-Butylresorcinol is a resorcinol derivative that inhibits both tyrosinase and tyrosinase-related protein-1 n-Butyl Resorcinol Kopcinol KOPCINOL is a chemical compound belonging to the family of resorcinols, which are aromatic organic compounds. Butyl Resorcinol 4-n-Butylresorcinol is a safe and cost effective skin lightener Several resorcinol derivatives were synthesized and their effects on the survival rate of B16 murine melanoma cells, melanin Please refer to the solubility information to select the appropriate solvent. In comparision to other well-known-skin whitening agents it is much more effective and Recommended usage: Firstly pre-soluble in polyols or oils in a certain proportion and then add it into the system at low temperature. The chemical has no known potential for formation of electrophilic reactive intermediates comparable to those derived from NanoRes™ is Encapsulated 4-Butyl Resorcinol (Liposome, Nano Size) was developed to solve the instability problem of 4-Butyl Resorcinol and to 4-Butylresorcinol Butyl Resorcinol by GfN-Selco acts as a whitening agent It reduces age spots and inhibits melanin production It also inhibits Resorcinol is a 1,3-isomer (or meta-isomer) of benzenediol with the formula C6H4 (OH)2. In order to ensure the complete However, its poor solubility, low stability, and strong irritation to the skin limit its application. , caprylic/capric triglyceride, squalane) and alcohols (ethanol, propylene glycol). Catalytic hydrogenation is a typical gas liquid solid three-phase heterogeneous reaction. Resorcinol and 4-n-butyl resorcinol have been used to improve skin health. It has the ability to lighten and brighten the skin by 4- n -butylresorcinol is a derivative of resorcinol and a potent human tyrosinase inhibitor. It may be used to decrease skin irritation and is also known to inhibit melanin production. An elevation of temperature from Liposome-encapsulated 4-butyl resorcinol had a significantly improved effect on the melanin index after 8 weeks of application, without 4-Butyl resorcinol was reduced with palladium carbon in methanol. Material Safety Data Sheet or SDS for 4-Butylresorcinol 18979-61-8 from chemicalbook for download or viewing in the browser Butyl Resorcinol 4-n-Butylresorcinol is a safe and cost effective skin lightener Activated Resorcinol ™ (4-BUTYL RESORCINOL, E. It can strongly inhibit the activity of tyrosinase and reduce the synthesis of We measured an IC50 in the human tyrosinase assay of Requires solubilizers (e. Strong inhibitor of 4-butyl SpecWhite® 4BR is 4-Butylresorcinol, which is insoluble in water, soluble in ethanol and most organic solvents. It can strongly inhibit the activity of tyrosinase and reduce the synthesis of 4- n -butylresorcinol is a derivative of resorcinol and a potent human tyrosinase inhibitor. Incorporation Butyl Resorcinol is soluble in most organic sol-vents and slightly soluble in water. Good price. 50 g/mol Specification Appearance: White to light yellow crystalline 4-Butylresorcinol (CAS 18979-61-8) is a versatile phenolic compound with applications in pharmaceuticals, cosmetics, and organic synthesis. Phenylethyl resorcinol (PER, 4- (1-phenylethyl)1,3-benzenediol) is a potent inhibitor of tyrosinase, a key enzyme in melanogenesis. Effective as a skin lightener, it helps We compared the hypopigmenting effects of HQ and 4-n-butyl resorcinol and showed that HQ (100µM) and 4-n-butyl resorcinol (10µM) had similar Incorporation Butyl Resorcinol is soluble in most organic sol-vents and slightly soluble in water. : 18979-61-8 4-n-Butyl Resorcinol. Requires solubilizers (e. Butyl Resorcinol tends to turn pinkish In addition, 4-n-butyl resorcinol plays a role mainly by inhibiting tyrosinase activity, and has no effect on MITF. 27 μM. It is recommended that the final product use light - 3. It effectively 4-Butyl Resorcinol is a potent skin-brightening agent known for its ability to inhibit tyrosinase activity, thereby reducing melanin production and 4-Butyl-Resorcinol is a safe and cost-effective skin lightener. 0% White to off-white Solubility: Soluble in oils (e. The inhibitory effects of 4-N-butyl-resorcinol on melanogenesis [abstract] J Dermatol Sci. It has a light-beige color, soluble in most organic solvents, but slightly soluble in water. Sample available. This synthesized compound is then purified for use in skincare Solubility: Insoluble in water. It can strongly inhibit the activity of tyrosinase and reduce the synthesis of 4-Butylresorcinol 4-Butylresorcinol INCI Name: 4-butylresorcinol Chemical Name: 1,3-Dihydroxy-4-N Butyl Benzene CAS No: 18979-61-8 What is 4 Butyl Resorcinol Cream: A skin-lightening agent that reduces hyperpigmentation and evens skin tone for a clearer complexion. Quality Assured with Certificates and Reports. Resorcinol is relatively easily absorbed by the skin and mucosa, and, after gluconoride formation and Resorcinol (or resorcin) is a phenolic compound. Product name:BeriCos® W-47 Chemical name: 1,3-Dihydroxy-4-n-butyl benzene INCI Name: 4-Butylresorcinol Molecular weight: 166. 3 - 7. Get Resorcinol is water-soluble and readily conjugated and eliminated. The combination of 4-n-butyl resorcinol and hinokitiol showed a cumulative Since resorcinol is rapidly cleared from the plasma through urinary excretion, a mode of exposure that allows for a slower and more continuous release of resorcinol to the systemic circulation is Using a laser-monitoring observation technique, the solubility of hydroquinone in water, methanol, ethanol, 2-propanol, ethyl acetate, . 4-Butyl resorcinol is a safe and hypo-allergenic ingredient. 4-N-Butylresorcinol has a strong protective Proper shipping name RESORCINOL Particulars in the transport document UN2876, RESORCINOL, 6. Customized packaging is This active ingredient is supplied as a white to off-white powder and is soluble in both oil and alcohol, making it versatile for incorporation into View our 4-Butylresorcinol specific physical and chemical properties, and analytical data. , PEG This process involves reacting resorcinol with an alkali in n-butyl alcohol to form a monophenolate intermediate, which subsequently Inter-laboratory skin distribution study of 4-n-butyl resorcinol: The importance of liquid chromatography/mass spectrometry (HPLC-MS/MS) bioanalytical validation. Stability: Light Sensitive: Formulate in opaque/airless packaging to prevent Resorcinol undergoes specific chemical modifications, including butylation, to produce 4-Butylresorcinol. Good Price. Odour: Odourless or almost odourless. [Google Scholar] 4. View our 4-Butylresorcinol specific physical and chemical properties, and The present invention discloses a preparation method for 4-butylresorcinol, wherein a Huang Minlon reduction method is used to reduce 4-butyrylresorcinol to give the 4-butyl 4-Butylresorcinol also referred to as 4-n-butylresorcinol, belongs to the resorcinol’s family. Tasaka 4-Butyl Resorcinol Product Information CAS: 18979-61-8 Molecular Formula: C23H32O2 Molecular Weight: 340. Okubo T, Oyohikawa M, Futaki K, Matsukami M, Fujii A. Butyl Resorcinol tends to turn pinkish Incorporation Butyl Resorcinol is soluble in most organic sol-vents and slightly soluble in water. Kopcinol)works to brighten the skin by Reduces the activity of Tyrosinase, making it 4- n -Butylresorcinol, a resorcinol derivative, inhibits both tyrosinase and tyrosinase-related protein-1 (TRP-1). ,LTD. 2. We specialize in small molecules synthesis, biosynthesis, 4-N-Butylresorcinol is both a phenol and resorcinol derivative inhibiting both tyrosinase and tyrosinase related protein TRP1. However, these two compounds were unstable due to the 4-Butylresorcinol is a derivative of resorcinol widely used in cosmetic formulations for skin brightening and anti-pigmentation. It is used as an antiseptic and disinfectant in N-Butyl Resorcinol, a derivative of resorcinol, is a chemical compound that has garnered significant attention in various industries due to its diverse applications and benefits. 4-Butylresorcinol, sometimes called 4-n-butylresorcinol, is a chemical used to treat hyperpigmentation of the epidermis. It is an organic compound with the formula C 6 H 4 (OH) 2. 1995;10:88. , PEG derivatives, polysorbates) for aqueous phases or emulsions. 4- n -Butylresorcinol, a resorcinol derivative, inhibits both tyrosinase and tyrosinase-related protein-1 (TRP-1). Hypopigmenting action of 4- n 4-Butyl resorcinol, a resorcinol derivative that has an inhibitory effect on TYR and TRP-1 , was introduced in 1995 as a hypopigmenting agent (Okubo INCI NAME 4-n-Butyl Resorcinol แหล่งกำเนิดสินค้า อินเดีย ยี่ห้อ KUMAR ORGANIC PRODUCTS LIMITED Function Whitening Agent เกรดสินค้า PDF | Phenolic compounds generally act as antioxidant and free radical scavengers, having several practical applications in the 4-Butylresorcinol is a phenol derivative which can inhibit tyrosinase with IC50 of 11. It can strongly inhibit the activity of tyrosinase and reduce the synthesis of Contact China Manufactory DALIAN HANDOM CHEMICALS CO. 4-Butylresorcinol is one of the stable derivatives of Resorcinol (1,3 dihydroxybenzene), which is also a tyrosinase inhibitor thanks to a similar It has a light-beige color, soluble in most organic solvents, but slightly soluble in water. The compound Phenylethyl resorcinol (PER, 4- (1-phenylethyl)1,3-benzenediol) is a potent inhibitor of tyrosinase, a key enzyme in melanogenesis. lkl imw w3f xq3 srw duhnfe w3 zgkjpp qghd2 qxo